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Intro: Delta and Omicron variants of SARS-CoV-2 are highly contagious, currently dominating the globe and recognized as variant of concern (VOC). The transmissibility efficiency of viruses, disease symptoms, and severity of COVID- 19 is highly heterogeneous. Therefore, testing at the community level is essential to identify the infected people at an early stage-carrying VOC to reduce the spread of virus and combat the pandemic. Method(s): In this study, we analysed thousands of genome sequences representing 30 different SARS-CoV-2 variants and identified Delta and Omicron variants specific nucleic acid signatures in the spike gene. Based on the variant specific nucleic acid sequences we synthesized different oligos and optimized a mPCR assay that can specifically differentiate the Delta and Omicron variants. We further translated our work into a dipstick assay (Tohoku Bio-array, Japan) by adding tag linker sequence to 5' end of the forward primer and adding biotin in 3' end of the oligos. Finding(s): A total of 250 samples were subjected to WGS using MiSeq platform and these confirmed samples were processed for validation of our specific designed probes using PCR assay and the readout was found to be 100% specific to Delta, BA.1 & BA.2 of SARS-CoV-2 variants which were further confirmed by Sanger sequencing. The dipstick was used to screen these samples, and specific signals were observed. WGS and Sanger sequencing were used to validate our PCR and dipstick assay results, and the readout was found to be 100% specific. The results can be visualised by the naked eye and interpreted easily. Conclusion(s): This study developed a rapid point-of-care test of SARS-CoV-2 patients, which can differentiate Delta, BA.1 and BA.2 variants at the same time of confirmation of the infection in patient. The current nucleic-acid chromatography-based dipstick assay is highly specific and can work even in the case of low viral load as well.Copyright © 2023
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Rotary Steerable Systems (RSS's) have proven beneficial over conventional steerable motor systems, which has driven significant market uptake over the last several decades. Consequently, applications for RSS's have expanded and encouraged RSS technology developers to meet these ever-changing market demands. Modifications to the basic proven RSS methods, attempted independent reproductions of those methods, and other novel methods have emerged to fulfill these market demands. The initial RSS method and technique were invented and proven in the late 1990s, and common ways of creating wellbore deflection emerged, allowing the industry to attempt the classification of these methods. These classifications were an attempt to gain a better understanding of the advantages and disadvantages of each and help understand where and what version of technology to apply for an ever-increasing expansion of applications. This paper describes the attempts at classification of RSS's, then addresses the drivers, development, and field trial results of a new method for placing wells using a high dogleg automated rotary steering system (SwR;Steering-while-Rotating). The SwR was targeted to meet market changes identified in 2016 and projected out ten (10) years by the SwR technical team. Simplicity, fostering reliability and value were major design tenets. A high dogleg curve (20°/100') design, enabling "one-run, Vertical, Curve, and Lateral" bottom hole assemblies, two-way (uplink-downlink) downhole communications along with autonomous self-steering capability, also drove the SwR development. The initial SwR prototype system for 8-3/8"-9-7/8" hole sizes was built, and field trials began in Q3 of 2019. The SwR team weathered the global Covid-19 pandemic of 2020-21 with the rest of the world and deployed systems to the Middle East, while also securing and executing trial and commercial runs within North America in 2021 and 2022. Conclusions are based upon, and data is presented from thirty-seven (37) bit runs and the first 50,000 feet drilled with the SwR. The SwR team has delivered a unique steering method to the industry and presents the early run data demonstrating the SwR technology capability to drill challenging well profiles, in challenging environments. The SwR technology was designed for the RSS market of today and for several years to come improving the value proposition for modern RSS well placement technology. Copyright © 2023, Society of Petroleum Engineers.
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In this paper, we present an information retrieval system on a corpus of scientific articles related to COVID-19. We build a similarity network on the articles where similarity is determined via shared citations and biological domain-specific sentence embeddings. Ego-splitting community detection on the article network is employed to cluster the articles and then the queries are matched with the clusters. Extractive summarization using BERT and PageRank methods is used to provide responses to the query. We also provide a Question-Answer bot on a small set of intents to demonstrate the efficacy of our model for an information extraction module. © ACL 2020.All right reserved.
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Purpose: Human history observed an arduous time fighting the novel infectious respiratory disease Covid-19 coronavirus, which started in Wuhan, China and spread rapidly across the globe in 2020. Economies and the countries including India around the world experienced dismay with nationwide lockdowns and the fear of the unknowing. The unforeseen circumstances enforced immediate transitions in the organizations' work environment through remote working, digital infrastructure, online collaborations and new ways of interaction. The pandemic altered the workplace trajectories in lasting ways as the employees settled into a new routine of working from home more quickly than imagined. Now, as India and many other countries slowly move beyond the crisis, there exists a need to realize the implications of the pandemic on the workplace and articulate the future of work. This article, therefore, investigates the key perceived benefits and the HR implications of the new and emerging concept of hybrid workplaces and presents an HRM framework for their successful adoption in India. The findings may prove crucial in framing new workplace norms and shaping them. Moreover, this research would provide practitioners, policymakers, business leaders and HR professionals insights about the need to review the existing workplaces and successfully roll out hybrid work models in accordance with HR strategies. Design/methodology/approach: The methodology of Systematic Review of Literature (SLR) was adopted to study the key perceived benefits and the HR implications of hybrid workplaces. Findings: The findings of the study would help business leaders, HR professionals, policymakers and researchers in developing HR policies and approaches for the adoption of the hybrid workplace as they chart the path toward the post-pandemic future. Research limitations/implications: The study stresses the HR implications of the future of work as the hybrid workplace paradigm evolves. The approach is explorative and would require quantitative validation in different sectors and countries. Originality/value: The study makes a direct link between the hybrid workplaces and the impetus for the transformation of HR strategies. It also examines the changing role of the human resources (HR) functions and professionals after the pandemic. © 2022, Emerald Publishing Limited.
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Purpose: Human history observed an arduous time fighting the novel infectious respiratory disease Covid-19 coronavirus, which started in Wuhan, China and spread rapidly across the globe in 2020. Economies and the countries including India around the world experienced dismay with nationwide lockdowns and the fear of the unknowing. The unforeseen circumstances enforced immediate transitions in the organizations' work environment through remote working, digital infrastructure, online collaborations and new ways of interaction. The pandemic altered the workplace trajectories in lasting ways as the employees settled into a new routine of working from home more quickly than imagined. Now, as India and many other countries slowly move beyond the crisis, there exists a need to realize the implications of the pandemic on the workplace and articulate the future of work. This article, therefore, investigates the key perceived benefits and the HR implications of the new and emerging concept of hybrid workplaces and presents an HRM framework for their successful adoption in India. The findings may prove crucial in framing new workplace norms and shaping them. Moreover, this research would provide practitioners, policymakers, business leaders and HR professionals insights about the need to review the existing workplaces and successfully roll out hybrid work models in accordance with HR strategies. Design/methodology/approach: The methodology of Systematic Review of Literature (SLR) was adopted to study the key perceived benefits and the HR implications of hybrid workplaces. Findings: The findings of the study would help business leaders, HR professionals, policymakers and researchers in developing HR policies and approaches for the adoption of the hybrid workplace as they chart the path toward the post-pandemic future. Research limitations/implications: The study stresses the HR implications of the future of work as the hybrid workplace paradigm evolves. The approach is explorative and would require quantitative validation in different sectors and countries. Originality/value: The study makes a direct link between the hybrid workplaces and the impetus for the transformation of HR strategies. It also examines the changing role of the human resources (HR) functions and professionals after the pandemic. © 2022, Emerald Publishing Limited.
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This case study is about Startup Incubation and Business Innovation Lab (SIBIL), an incubation center working toward the implementation of startup policy in India. SIBIL provides support and guidance for the growth and business development of the new innovative start-ups located across India. It provides support for mobilizing seed funds, angel investors and firm spin-off apart from providing marketing expertise for commercialization of products and marketing research. This case has been written in the times when COVID-19 has brought various opportunities and threats to the start-ups and hence it is challenging for incubators to draw future action plans. The biggest challenge has been seen in terms of maintaining sustenance of start-ups. This case highlights two companies facing similar problems and draws future scenarios for them. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.
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The aim of this mini-review is to explore the potential of indigenous photocatalytic assisted microwave plasma based pyrolyser for COVID-19 related wastes (gloves, masks, bottles, personal protective equipment (PPE), etc.) conversion into liquid oil. Plasma pyrolysis can provide solution for complete pyrolysis of typical hospital wastes not limited to PPE wastes. Literature survey reveals that pyrolysis of polystyrene (PS) plastic waste feedstock can yield up to 80% of pyrolytic oil including styrene, ethylbenzene and toluene with their physico-chemical properties such as density, viscosity, flash point, freezing point, pour point, and high heating values very similar to the conventional diesel and therefore, possess potential as an alternative source for power generation. It is suggested that char produced from pyrolysis has requisite properties for electro-oxidation of CO2. Moreover, if such a system could be integrated with a microwave heating process having absorbents like silicon carbide and different catalyst combinations, up to 32% energy saving could be done in the process that would be rapid, uniform and energy-efficient.
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In 2019 the novel Corona virus which is called COVID 19 was originated in China and now it has spread all over the world. So far more than 73M people got affected all over the world, most of the countries are searching for easy way to analyze. The increasing number of daily COVID 19 cases needs another solution and needs a lot of study. In this paper a deep learning model has been proposed for detection and classification of COVID 19 with high accuracy from chest x-ray. The tensor flow based CNN method has been proposed to classify using chest x-ray images. The proposed model has been trained and tested on the prepared dataset and it has been found that the overall accuracy achieved for the 2-class classification (COVID 19 vs Healthy) is 95%, and the precision and recall rate are 95%. The performance of the proposed model is very promising and it can be very helpful tool for radiologists and clinical practitioners in case of COVID 19 detection and classification because of its simplicity. More over this paper represent a comparative study of the proposed technique with ELM which will help researchers for further analysis.
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SARS-CoV-2, the causative agent for COVID-19, originated in China in the fall of 2019 and soon became a pandemic engulfing the entire world, presenting with a myriad of presentations from asymptomatic to severe disease with acute respiratory distress syndrome and multiple organ dysfunction and severe inflammatory response. Little is understood about the new virus and its pathogenesis, and it is too early to ascertain its long-term sequelae at this point in time. New associations and clinical problems keep appearing with the new virus and thus we also got to encounter three cases of acute inflammatory demyelinating polyneuropathy (AIDP) in patients following COVID-19 infection. This case series aims to convey clinicians that AIDP can be seen in patients with COVID-19, particularly during the recovery phase, and thus not to miss it as postviral fatigue and malaise.
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Digital forms of money have turned into the most discussed issue in the budgetary business due to probable transmission of COVID-19 through coins and bank notes. A digital money is a computerized or virtual cash that utilizes cryptography for security. Digital money is hard to follow considering its security. A characterizing highlight of a digital money is that it is not issued by any focal specialist, rendering it hypothetically safe to government impedance or control. Digital currencies have their advantages and disadvantages. This paper explains distinctive components of digital currencies, beginning with their initial advancement, difficulties and threats associated with them, points of interest and weaknesses, and their future managing issues identified with the down to earth capacity of cryptographic forms of money. It was presumed that it is difficult to anticipate the eventual fate of cryptographic forms of money as it is yet to be created. The banks and other monetary based organizations may analyze digital currencies as an option for the monetary exchanges later. © 2020 IEEE.